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What Is Bad In Akt Pathway? [Solved]

Akt negatively regulates pro-apoptotic proteins by direct phosphorylation. For example, phosphorylation of BAD, the Bcl-2 family member, on Ser136 causes translocation from the mitochondrial membrane to the cytosol, where it is sequestered by 14-3-3 proteins.

PI3K-AKT Pathway Explained

Many growth factors, hormones, cytokines, and nutrients activate the phosphoinositide 3-kinase (PI3K)/protein kinase B (

AKT Signaling Pathway | Regulation and Downstream Effects

Biomedical lesson on

Akt pathway

Akt pathway