Howdy, iam David Grimes, G’day, mate.
What Is Bad In Akt Pathway? [Solved]
Akt negatively regulates pro-apoptotic proteins by direct phosphorylation. For example, phosphorylation of BAD, the Bcl-2 family member, on Ser136 causes translocation from the mitochondrial membrane to the cytosol, where it is sequestered by 14-3-3 proteins.
PI3K-AKT Pathway Explained
Many growth factors, hormones, cytokines, and nutrients activate the phosphoinositide 3-kinase (PI3K)/protein kinase B (
AKT Signaling Pathway | Regulation and Downstream Effects
Biomedical lesson on
Akt pathway
Akt pathway